Peripheral follicular helper T cells in acute viral diseases: a perspective on dengue.
Future Virol
; 14(3): 161-169, 2019 Mar.
Article
en En
| MEDLINE
| ID: mdl-31073324
ABSTRACT
Follicular helper T cells (TFH) are a predominant subset of CD4+ T cells specialized in providing help to B cells in germinal centers and necessary to generate T cell-dependent antibody responses. Peripheral TFH (pTFH) are the counterpart of TFH found in the circulation, which resemble TFH in many aspects of their phenotype and function. The CD4+ pTFH subset has received a lot of interest recently because they are easy to access and have the potential to serve as a biomarker for long-lasting humoral immunity. This review will discuss recent findings of pTFH in human acute viral diseases with a focus on dengue infection.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Future Virol
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos