Inhibition of lncRNA TUG1 upregulates miR-142-3p to ameliorate myocardial injury during ischemia and reperfusion via targeting HMGB1- and Rac1-induced autophagy.

Su, Qiang; Liu, Yang; Lv, Xiang-Wei; Ye, Zi-Liang; Sun, Yu-Han; Kong, Bing-Hui; Qin, Zhen-Bai

Su, Qiang; Liu, Yang; Lv, Xiang-Wei; Ye, Zi-Liang; Sun, Yu-Han; Kong, Bing-Hui; Qin, Zhen-Bai.

Afiliación

Su Q; Department of Cardiology, The Affiliated Hospital of Guilin Medical University, Guilin 541001, PR China. Electronic address: suqiang1983@foxmail.com.
Liu Y; Department of Cardiology, The Second People's Hospital of Nanning City, The Third Affiliated Hospital of Guangxi Medical University, Nanning 530031, PR China.
Lv XW; Department of Cardiology, The Affiliated Hospital of Guilin Medical University, Guilin 541001, PR China.
Ye ZL; Department of Cardiology, The Affiliated Hospital of Guilin Medical University, Guilin 541001, PR China.
Sun YH; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, PR China.
Kong BH; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, PR China.
Qin ZB; Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, PR China.

J Mol Cell Cardiol ; 133: 12-25, 2019 08.

Article en En | MEDLINE | ID: mdl-31145943

Asunto(s)

Autofagia/genética; Proteína HMGB1/genética; MicroARNs/genética; Daño por Reperfusión Miocárdica/genética; ARN Largo no Codificante/genética; Proteína de Unión al GTP rac1/genética; Regiones no Traducidas 3'; Animales; Línea Celular Tumoral; Proliferación Celular/genética; Modelos Animales de Enfermedad; Técnicas de Silenciamiento del Gen; Silenciador del Gen; Humanos; Hipoxia/genética; Ratones; Daño por Reperfusión Miocárdica/patología; Miocitos Cardíacos/metabolismo

Palabras clave

Autophagy; Hypoxia; Ischemia/reperfusion; TUG1; miR-142-3p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Daño por Reperfusión Miocárdica / Proteína de Unión al GTP rac1 / Proteína HMGB1 / MicroARNs / ARN Largo no Codificante Límite: Animals / Humans Idioma: En Revista: J Mol Cell Cardiol Año: 2019 Tipo del documento: Article

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