Type I interferon induced by TLR2-TLR4-MyD88-TRIF-IRF3 controls Mycobacterium abscessus subsp. abscessus persistence in murine macrophages via nitric oxide.

Ruangkiattikul, Nanthapon; Rys, Doris; Abdissa, Ketema; Rohde, Manfred; Semmler, Torsten; Tegtmeyer, Pia-K; Kalinke, Ulrich; Schwarz, Carsten; Lewin, Astrid; Goethe, Ralph

Ruangkiattikul, Nanthapon; Rys, Doris; Abdissa, Ketema; Rohde, Manfred; Semmler, Torsten; Tegtmeyer, Pia-K; Kalinke, Ulrich; Schwarz, Carsten; Lewin, Astrid; Goethe, Ralph.

Afiliación

Ruangkiattikul N; Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany.
Rys D; Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany.
Abdissa K; Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany.
Rohde M; Central Facility for Microscopy, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Semmler T; NG1 Microbial Genomics, Robert Koch Institute, Berlin, Germany.
Tegtmeyer PK; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, A Joint Venture Between The Helmholtz Centre for Infection Research, Braunschweig, and The Hannover Medical School, Hannover, Germany.
Kalinke U; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, A Joint Venture Between The Helmholtz Centre for Infection Research, Braunschweig, and The Hannover Medical School, Hannover, Germany.
Schwarz C; Department of Pediatric Pneumonology and Immunology, Division of Cystic Fibrosis, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Lewin A; FG16 Mycotic and Parasitic Agents and Mycobacteria, Robert Koch Institute, Berlin, Germany.
Goethe R; Institute for Microbiology, University of Veterinary Medicine Hannover, Hannover, Germany. Electronic address: ralph.goethe@tiho-hannover.de.

Int J Med Microbiol ; 309(5): 307-318, 2019 Jul.

Article en En | MEDLINE | ID: mdl-31178418

Asunto(s)

Interferón beta/inmunología; Macrófagos/microbiología; Mycobacterium abscessus/inmunología; Factor 88 de Diferenciación Mieloide/inmunología; Óxido Nítrico/inmunología; Receptor Toll-Like 2/inmunología; Receptor Toll-Like 4/inmunología; Animales; Interacciones Huésped-Patógeno/inmunología; Humanos; Macrófagos/inmunología; Ratones; Ratones Endogámicos C57BL; Infecciones por Mycobacterium no Tuberculosas/inmunología; Infecciones por Mycobacterium no Tuberculosas/microbiología; Óxido Nítrico Sintasa de Tipo II/genética; Esputo/microbiología

Palabras clave

Bacterial clearance; Cystic fibrosis; Inducible nitric oxide synthase; Interferon-ß; Macrophage; Non-tuberculous mycobacteria

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Interferón beta / Receptor Toll-Like 2 / Receptor Toll-Like 4 / Factor 88 de Diferenciación Mieloide / Mycobacterium abscessus / Macrófagos / Óxido Nítrico Límite: Animals / Humans Idioma: En Revista: Int J Med Microbiol Asunto de la revista: MICROBIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Alemania

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