Serological evidence of Zika virus infection in febrile patients at Greater Accra Regional Hospital, Accra Ghana.
BMC Res Notes
; 12(1): 326, 2019 Jun 10.
Article
en En
| MEDLINE
| ID: mdl-31182146
ABSTRACT
OBJECTIVE:
Increase in the evidence of global occurrence of Zika viral infection suggests that in Africa the circulation of the virus which causes 80% of asymptomatic infection could be undetected and/or overlooked. We sought to serologically detect Zika virus infection in febrile patients at Greater Accra Regional Hospital, Ghana.RESULTS:
Of the 160 patient serum samples analyzed, 33 were found to have antibodies against Zika virus infection. Among the sero-positives 30 (91%) of the cases were anti-Zika virus IgM with the 21-30-year age group recording the highest number of 8 (26%) and 2 (7%) cases being the least for the 61 years and above age group. All sero-positive febrile patients developed at least one symptom consistent with Zika virus infection 33 (100%) fever, 25 (76%) muscle pain, 24 (73%) joint pain, and conjunctivitis 2 (6%). Digestive symptoms recorded include 16 (49%) nausea, 12 (36%) vomiting and diarrhea 18 (55%). In addition, 28 (85%) loss of appetite, 14 (75%) rapid respiration and chest pain 15 (42%) were reported by seropositive febrile patients. Our data indicates exposure to Zika virus which suggests the possible circulation of the virus among febrile patients in Ghana with a sero-prevalence rate of 20.6%.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Artralgia
/
Fiebre
/
Mialgia
/
Virus Zika
/
Infección por el Virus Zika
/
Anticuerpos Antivirales
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
País/Región como asunto:
Africa
Idioma:
En
Revista:
BMC Res Notes
Año:
2019
Tipo del documento:
Article
País de afiliación:
Ghana