Structurally-defined deubiquitinase inhibitors provide opportunities to investigate disease mechanisms.

Wertz, Ingrid E; Murray, Jeremy M

Wertz, Ingrid E; Murray, Jeremy M.

Afiliación

Wertz IE; Department of Discovery Oncology, Genentech, Inc. 1 DNA Way, South San Francisco, 94080, USA; Department of Early Discovery Biochemistry, Genentech, Inc. 1 DNA Way, South San Francisco, 94080, USA. Electronic address: ingrid@gene.com.
Murray JM; Department of Structural Biology, Genentech, Inc. 1 DNA Way, South San Francisco, 94080, USA. Electronic address: murray.jeremy@gene.com.

Drug Discov Today Technol ; 31: 109-123, 2019 Apr.

Article en En | MEDLINE | ID: mdl-31200854

Asunto(s)

Pirroles/farmacología; Ubiquitina Tiolesterasa/antagonistas & inhibidores; Animales; Humanos; Estructura Molecular; Pirroles/química; Ubiquitina Tiolesterasa/química; Ubiquitina Tiolesterasa/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirroles / Ubiquitina Tiolesterasa Límite: Animals / Humans Idioma: En Revista: Drug Discov Today Technol Año: 2019 Tipo del documento: Article

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