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Gastrointestinal Polyposis in Pediatric Patients.
MacFarland, Suzanne P; Zelley, Kristin; Katona, Bryson W; Wilkins, Benjamin J; Brodeur, Garrett M; Mamula, Petar.
Afiliación
  • MacFarland SP; Division of Oncology, Department of Pediatrics.
  • Zelley K; Division of Oncology, Department of Pediatrics.
  • Katona BW; Division of Gastroenterology, Department of Medicine.
  • Wilkins BJ; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia.
  • Brodeur GM; Division of Oncology, Department of Pediatrics.
  • Mamula P; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
J Pediatr Gastroenterol Nutr ; 69(3): 273-280, 2019 09.
Article en En | MEDLINE | ID: mdl-31211762
Gastrointestinal polyps are mucosal overgrowths that, if unchecked, can undergo malignant transformation. Although relatively uncommon in the pediatric age group, they can be the harbingers of multiorgan cancer risk and require close management and follow-up. Additionally, as many polyposis syndromes are inherited, appropriate genetic testing and management of relatives is vital for the health of the entire family. In this review, we discuss both common and uncommon childhood gastrointestinal polyposis syndromes in terms of clinical presentation, management, and surveillance. We also detail any additional malignancy risk and surveillance required in the pediatric age group (<21 years old). Through this review, we provide a framework for gastroenterologists to manage the multifaceted nature of pediatric polyposis syndromes.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Peutz-Jeghers / Poliposis Adenomatosa del Colon / Predisposición Genética a la Enfermedad / Neoplasias Gastrointestinales Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2019 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndrome de Peutz-Jeghers / Poliposis Adenomatosa del Colon / Predisposición Genética a la Enfermedad / Neoplasias Gastrointestinales Tipo de estudio: Guideline / Prognostic_studies Límite: Adolescent / Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2019 Tipo del documento: Article