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Phenotyping an adult zebrafish lamp2 cardiomyopathy model identifies mTOR inhibition as a candidate therapy.
Dvornikov, Alexey V; Wang, Mingmin; Yang, Jingchun; Zhu, Ping; Le, Tai; Lin, Xueying; Cao, Hung; Xu, Xiaolei.
Afiliación
  • Dvornikov AV; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Wang M; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA; Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
  • Yang J; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Zhu P; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Le T; Department of Electrical Engineering and Computer Science, University of California Irvine, CA, USA.
  • Lin X; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Cao H; Department of Electrical Engineering and Computer Science, University of California Irvine, CA, USA; Department of Biomedical Engineering, University of California Irvine, CA, USA.
  • Xu X; Department of Biochemistry and Molecular Biology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: xu.xiaolei@mayo.edu.
J Mol Cell Cardiol ; 133: 199-208, 2019 08.
Article en En | MEDLINE | ID: mdl-31228518
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenotipo / Pez Cebra / Enfermedad por Depósito de Glucógeno de Tipo IIb / Proteína 2 de la Membrana Asociada a los Lisosomas / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Mol Cell Cardiol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenotipo / Pez Cebra / Enfermedad por Depósito de Glucógeno de Tipo IIb / Proteína 2 de la Membrana Asociada a los Lisosomas / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Mol Cell Cardiol Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos