Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution.

Hosein, Abdel Nasser; Huang, Huocong; Wang, Zhaoning; Parmar, Kamalpreet; Du, Wenting; Huang, Jonathan; Maitra, Anirban; Olson, Eric; Verma, Udit; Brekken, Rolf A

Hosein, Abdel Nasser; Huang, Huocong; Wang, Zhaoning; Parmar, Kamalpreet; Du, Wenting; Huang, Jonathan; Maitra, Anirban; Olson, Eric; Verma, Udit; Brekken, Rolf A.

Afiliación

Hosein AN; Hamon Center for Therapeutic Oncology Research, Division of Surgical Oncology, Department of Surgery, and.
Huang H; Division of Hematology & Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Wang Z; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Parmar K; Hamon Center for Therapeutic Oncology Research, Division of Surgical Oncology, Department of Surgery, and.
Du W; Department of Molecular Biology and.
Huang J; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Maitra A; Hamon Center for Therapeutic Oncology Research, Division of Surgical Oncology, Department of Surgery, and.
Olson E; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Verma U; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Brekken RA; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

JCI Insight ; 52019 07 23.

Article en En | MEDLINE | ID: mdl-31335328

Asunto(s)

Carcinoma Ductal Pancreático/genética; Heterogeneidad Genética; Neoplasias Pancreáticas/genética; Análisis de la Célula Individual/métodos; Animales; Carcinoma Ductal Pancreático/metabolismo; Carcinoma Ductal Pancreático/patología; Modelos Animales de Enfermedad; Epigenómica; Fibroblastos; Regulación Neoplásica de la Expresión Génica; Predisposición Genética a la Enfermedad/genética; Ratones; Ratones Endogámicos C57BL; Mutación; Neoplasias Pancreáticas/metabolismo; Neoplasias Pancreáticas/patología; Análisis de Secuencia; Transcriptoma

Palabras clave

Cancer; Gastroenterology; Oncology

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Heterogeneidad Genética / Carcinoma Ductal Pancreático / Análisis de la Célula Individual Límite: Animals Idioma: En Revista: JCI Insight Año: 2019 Tipo del documento: Article

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