Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site.

Beyer, Hannes M; Mikula, Kornelia M; Kudling, Tatiana V; Iwaï, Hideo

Beyer, Hannes M; Mikula, Kornelia M; Kudling, Tatiana V; Iwaï, Hideo.

Afiliación

Beyer HM; Research Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland.
Mikula KM; Research Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland.
Kudling TV; Research Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland.
Iwaï H; Research Program in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, P.O. Box 65, 00014, Helsinki, Finland. hideo.iwai@helsinki.fi.

Extremophiles ; 23(6): 669-679, 2019 Nov.

Article en En | MEDLINE | ID: mdl-31363851

Asunto(s)

Proteínas Arqueales/química; Endonucleasas/química; Inteínas; Pyrococcus abyssi/enzimología; Pyrococcus horikoshii/enzimología; Proteínas Arqueales/genética; Endonucleasas/genética; Estabilidad de Enzimas; Calor; Dominios Proteicos; Pyrococcus abyssi/genética; Pyrococcus horikoshii/genética

Palabras clave

Homing endonuclease; Horizontal gene transfer; Hyperthermophiles; Inteins; Protein splicing

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Arqueales / Pyrococcus abyssi / Pyrococcus horikoshii / Inteínas / Endonucleasas Idioma: En Revista: Extremophiles Asunto de la revista: BIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Finlandia

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