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WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.
Chen, Huimei; Moreno-Moral, Aida; Pesce, Francesco; Devapragash, Nithya; Mancini, Massimiliano; Heng, Ee Ling; Rotival, Maxime; Srivastava, Prashant K; Harmston, Nathan; Shkura, Kirill; Rackham, Owen J L; Yu, Wei-Ping; Sun, Xi-Ming; Tee, Nicole Gui Zhen; Tan, Elisabeth Li Sa; Barton, Paul J R; Felkin, Leanne E; Lara-Pezzi, Enrique; Angelini, Gianni; Beltrami, Cristina; Pravenec, Michal; Schafer, Sebastian; Bottolo, Leonardo; Hubner, Norbert; Emanueli, Costanza; Cook, Stuart A; Petretto, Enrico.
Afiliación
  • Chen H; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Moreno-Moral A; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Pesce F; Department of Emergency and Organ Transplantation (DETO), University of Bari, 70124, Bari, Italy.
  • Devapragash N; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Mancini M; SOC di Anatomia Patologica, Ospedale San Giovanni di Dio, 50123, Florence, Italy.
  • Heng EL; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Rotival M; Unit of Human Evolutionary Genetics, Institute Pasteur, 75015, Paris, France.
  • Srivastava PK; Division of Brain Sciences, Imperial College Faculty of Medicine, London, W12 0NN, UK.
  • Harmston N; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Shkura K; Division of Brain Sciences, Imperial College Faculty of Medicine, London, W12 0NN, UK.
  • Rackham OJL; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Yu WP; Animal Gene Editing Laboratory, BRC, A*STAR20 Biopolis Way, Singapore, 138668, Republic of Singapore.
  • Sun XM; Institute of Molecular and Cell Biology, A*STAR, 61 Biopolis Drive, Singapore, 138673, Republic of Singapore.
  • Tee NGZ; MRC London Institute of Medical Sciences (LMC), Imperial College, London, W12 0NN, UK.
  • Tan ELS; National Heart Centre Singapore, Singapore, 169609, Republic of Singapore.
  • Barton PJR; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Felkin LE; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Lara-Pezzi E; Cardiovascular Research Centre, Royal Brompton and Harefield NHS Trust, London, SW3 6NP, UK.
  • Angelini G; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Beltrami C; Cardiovascular Research Centre, Royal Brompton and Harefield NHS Trust, London, SW3 6NP, UK.
  • Pravenec M; Centro Nacional de Investigaciones Cardiovasculares - CNIC, 28029, Madrid, Spain.
  • Schafer S; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Bottolo L; Bristol Heart Institute, Bristol Medical School, University of Bristol, Bristol, BS2 89HW, UK.
  • Hubner N; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Emanueli C; Institute of Physiology, Czech Academy of Sciences, 142 00, Praha 4, Czech Republic.
  • Cook SA; Programme in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, 169857, Republic of Singapore.
  • Petretto E; National Heart Centre Singapore, Singapore, 169609, Republic of Singapore.
Nat Commun ; 10(1): 3616, 2019 08 09.
Article en En | MEDLINE | ID: mdl-31399586
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrosis / Predisposición Genética a la Enfermedad / Ubiquitina-Proteína Ligasas / Proteína Smad2 / Redes Reguladoras de Genes Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrosis / Predisposición Genética a la Enfermedad / Ubiquitina-Proteína Ligasas / Proteína Smad2 / Redes Reguladoras de Genes Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article