A Membrane-Anchored Short-Peptide Fusion Inhibitor Fully Protects Target Cells from Infections of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.

Tang, Xiaoran; Jin, Hongliang; Chen, Yue; Li, Li; Zhu, Yuanmei; Chong, Huihui; He, Yuxian

Tang, Xiaoran; Jin, Hongliang; Chen, Yue; Li, Li; Zhu, Yuanmei; Chong, Huihui; He, Yuxian.

Afiliación

Tang X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jin H; Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li L; Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhu Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chong H; Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
He Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

J Virol ; 93(22)2019 11 15.

Article en En | MEDLINE | ID: mdl-31462566

Asunto(s)

Inhibidores de Fusión de VIH/farmacología; Internalización del Virus/efectos de los fármacos; Linfocitos T CD4-Positivos/virología; Membrana Celular/metabolismo; Glicosilfosfatidilinositoles/farmacología; Células HEK293; Infecciones por VIH/virología; VIH-1/efectos de los fármacos; VIH-2/efectos de los fármacos; Humanos; Fusión de Membrana/efectos de los fármacos; Fragmentos de Péptidos/metabolismo; Péptidos/farmacología; Receptores CCR5/metabolismo; Receptores CXCR4/metabolismo; Virus de la Inmunodeficiencia de los Simios/efectos de los fármacos

Palabras clave

HIV-1; HIV-2; fusion inhibitor; gene therapy; glycosylphosphatidylinositol

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Fusión de VIH / Internalización del Virus Límite: Humans Idioma: En Revista: J Virol Año: 2019 Tipo del documento: Article País de afiliación: China

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