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Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI.
Georgi, Benjamin; Mielke, Johanna; Chaffin, Mark; Khera, Amit V; Gelis, Lian; Mundl, Hardi; van Giezen, J J J; Ellinor, Patrick; Kathiresan, Sekar; Ziegelbauer, Karl; Freitag, Daniel F.
Afiliación
  • Georgi B; From the Bayer Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany (B.G., J.M., K.Z., D.F.F.).
  • Mielke J; From the Bayer Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany (B.G., J.M., K.Z., D.F.F.).
  • Chaffin M; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA (M.C., A.V.K., P.E., S.K.).
  • Khera AV; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA (M.C., A.V.K., P.E., S.K.).
  • Gelis L; Bayer Pharmaceuticals, Clinical Development, Wuppertal, Germany (L.G., H.M., J.J.J.v.G.).
  • Mundl H; Bayer Pharmaceuticals, Clinical Development, Wuppertal, Germany (L.G., H.M., J.J.J.v.G.).
  • van Giezen JJJ; Bayer Pharmaceuticals, Clinical Development, Wuppertal, Germany (L.G., H.M., J.J.J.v.G.).
  • Ellinor P; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA (M.C., A.V.K., P.E., S.K.).
  • Kathiresan S; Cardiovascular Disease Initiative, Broad Institute of Harvard and MIT, Cambridge, MA (M.C., A.V.K., P.E., S.K.).
  • Ziegelbauer K; From the Bayer Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany (B.G., J.M., K.Z., D.F.F.).
  • Freitag DF; From the Bayer Pharmaceuticals, Open Innovation & Digital Technologies, Wuppertal, Germany (B.G., J.M., K.Z., D.F.F.).
Stroke ; 50(11): 3004-3012, 2019 11.
Article en En | MEDLINE | ID: mdl-31558144
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Factor XI / Bancos de Muestras Biológicas / Trombosis de la Vena / Accidente Cerebrovascular / Hemorragia Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Stroke Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Factor XI / Bancos de Muestras Biológicas / Trombosis de la Vena / Accidente Cerebrovascular / Hemorragia Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Stroke Año: 2019 Tipo del documento: Article