Neonatal pharmacology and clinical implications.
Drugs Context
; 8: 212608, 2019.
Article
en En
| MEDLINE
| ID: mdl-31692800
ABSTRACT
During the neonatal period, there is physiological immaturity of organs, systems and metabolic pathways that influences the pharmacokinetics and pharmacodynamics of administered drugs, the dosage of which should be constantly amended, considering the progressive increase in weight and the maturation of the elimination pathways. In this article, we analyse the main pharmacokinetic aspects (absorption, distribution, metabolism and excretion) that exist during the neonatal period, to offer a description of the physiological background for variability in pharmacological dosing.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Drugs Context
Año:
2019
Tipo del documento:
Article
País de afiliación:
Italia