Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-ß from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer.

Singha, Prajjal K; Pandeswara, Srilakshmi; Geng, Hui; Lan, Rongpei; Venkatachalam, Manjeri A; Dobi, Albert; Srivastava, Shiv; Saikumar, Pothana

Singha, Prajjal K; Pandeswara, Srilakshmi; Geng, Hui; Lan, Rongpei; Venkatachalam, Manjeri A; Dobi, Albert; Srivastava, Shiv; Saikumar, Pothana.

Afiliación

Singha PK; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.
Pandeswara S; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.
Geng H; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.
Lan R; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.
Venkatachalam MA; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.
Dobi A; Department of Pathology, Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Srivastava S; Department of Pathology, Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Saikumar P; Department of Med/Hematology & Med Oncology, UT Health Science Center at San Antonio, TX, USA.

Genes Cancer ; 10(5-6): 134-149, 2019.

Article en En | MEDLINE | ID: mdl-31798766

Palabras clave

PTEN; Smad2; Smad3; TGF-ß; TMEPAI

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Genes Cancer Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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