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Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type.
Franco, Irene; Helgadottir, Hafdis T; Moggio, Aldo; Larsson, Malin; Vrtacnik, Peter; Johansson, Anna; Norgren, Nina; Lundin, Pär; Mas-Ponte, David; Nordström, Johan; Lundgren, Torbjörn; Stenvinkel, Peter; Wennberg, Lars; Supek, Fran; Eriksson, Maria.
Afiliación
  • Franco I; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden. irene.franco@ki.se.
  • Helgadottir HT; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Moggio A; Department of Medicine Huddinge, Integrated Cardio Metabolic Center, Karolinska Institutet, Huddinge, Sweden.
  • Larsson M; Science for Life Laboratory, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden.
  • Vrtacnik P; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Johansson A; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
  • Norgren N; Science for Life Laboratory, Department of Molecular Biology, Umeå University, Umeå, Sweden.
  • Lundin P; Department of Biosciences and Nutrition, Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Mas-Ponte D; Science for Life Laboratory, Department of Biochemistry and Biophysics (DBB), Stockholm University, Stockholm, Sweden.
  • Nordström J; Genome Data Science, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028, Barcelona, Spain.
  • Lundgren T; Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Transplantation Surgery, Karolinska University Hospital, Huddinge, Sweden.
  • Stenvinkel P; Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Transplantation Surgery, Karolinska University Hospital, Huddinge, Sweden.
  • Wennberg L; Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Renal Medicine, Karolinska University Hospital, Huddinge, Sweden.
  • Supek F; Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Division of Transplantation Surgery, Karolinska University Hospital, Huddinge, Sweden.
  • Eriksson M; Genome Data Science, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028, Barcelona, Spain.
Genome Biol ; 20(1): 285, 2019 12 18.
Article en En | MEDLINE | ID: mdl-31849330
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mutagénesis / Secuenciación Completa del Genoma / Neoplasias Límite: Aged / Female / Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Suecia
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mutagénesis / Secuenciación Completa del Genoma / Neoplasias Límite: Aged / Female / Humans Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Suecia