Back to the Future: Effector Fate during T Cell Exhaustion.

Buchholz, Veit R; Busch, Dirk H

Buchholz, Veit R; Busch, Dirk H.

Afiliación

Buchholz VR; Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany. Electronic address: veit.buchholz@tum.de.
Busch DH; Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany; German Center for Infection Research (DZIF), Partner site Munich, Germany. Electronic address: dirk.busch@tum.de.

Immunity ; 51(6): 970-972, 2019 12 17.

Article en En | MEDLINE | ID: mdl-31851902

ABSTRACT

ABSTRACT

Exhausted CD8+ T cells adopt a functionally attenuated state but still confer a certain degree of pathogen control. Chen et al. (2019), Hudson et al. (2019), and Zander et al. (2019) assign the lasting maintenance of this restrained pathogen control to an equilibrium of effector-like, transitory, terminal, and memory-like exhausted T cells.

Asunto(s)

Linfocitos T CD8-positivos; Redes Reguladoras de Genes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Redes Reguladoras de Genes Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article

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