A novel UPLC/MS/MS method for rapid determination of murrayone in rat plasma and its pharmacokinetics.

Zhai, Shengyi; Deng, Xiaoxiao; Zhang, Chen; Zhou, Yu; Xie, Huanzhang; Jiang, Zhou; Jia, Lee

Zhai, Shengyi; Deng, Xiaoxiao; Zhang, Chen; Zhou, Yu; Xie, Huanzhang; Jiang, Zhou; Jia, Lee.

Afiliación

Zhai S; Sunlight Building, Science Park, 2 Xueyuan Road, University Town, Cancer Metastasis Alert and Prevention Center, Fuzhou University, Fuzhou, Fujian 350116, China.
Deng X; Sunlight Building, Science Park, 2 Xueyuan Road, University Town, Cancer Metastasis Alert and Prevention Center, Fuzhou University, Fuzhou, Fujian 350116, China.
Zhang C; Institute of Oceanography, Minjiang University, Fuzhou, Fujian 350108, China.
Zhou Y; Sunlight Building, Science Park, 2 Xueyuan Road, University Town, Cancer Metastasis Alert and Prevention Center, Fuzhou University, Fuzhou, Fujian 350116, China.
Xie H; Institute of Oceanography, Minjiang University, Fuzhou, Fujian 350108, China.
Jiang Z; Sunlight Building, Science Park, 2 Xueyuan Road, University Town, Cancer Metastasis Alert and Prevention Center, Fuzhou University, Fuzhou, Fujian 350116, China. Electronic address: jiang_zhou@fzu.edu.cn.
Jia L; Sunlight Building, Science Park, 2 Xueyuan Road, University Town, Cancer Metastasis Alert and Prevention Center, Fuzhou University, Fuzhou, Fujian 350116, China; Institute of Oceanography, Minjiang University, Fuzhou, Fujian 350108, China. Electronic address: cmapcjia1234@163.com.

J Pharm Biomed Anal ; 180: 113046, 2020 Feb 20.

Article en En | MEDLINE | ID: mdl-31874311

Asunto(s)

Antineoplásicos/química; Antineoplásicos/farmacocinética; Cumarinas/química; Cumarinas/farmacocinética; Medicamentos Herbarios Chinos/química; Medicamentos Herbarios Chinos/farmacocinética; Metabolómica/métodos; Tracheophyta/química; Animales; Cromatografía Líquida de Alta Presión; Ensayos de Selección de Medicamentos Antitumorales; Estabilidad de Medicamentos; Femenino; Límite de Detección; Modelos Lineales; Masculino; Medicina Tradicional China; Plasma/química; Ratas; Ratas Sprague-Dawley; Reproducibilidad de los Resultados; Espectrometría de Masas en Tándem

Palabras clave

Cancer metastasis chemopreventive agent; Murraya paniculata (L.); Murrayone; Pharmacokinetics; UPLC/MS/MS

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Cumarinas / Metabolómica / Tracheophyta / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2020 Tipo del documento: Article País de afiliación: China

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