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In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors.
Nass, Karol; Redecke, Lars; Perbandt, M; Yefanov, O; Klinge, M; Koopmann, R; Stellato, F; Gabdulkhakov, A; Schönherr, R; Rehders, D; Lahey-Rudolph, J M; Aquila, A; Barty, A; Basu, S; Doak, R B; Duden, R; Frank, M; Fromme, R; Kassemeyer, S; Katona, G; Kirian, R; Liu, H; Majoul, I; Martin-Garcia, J M; Messerschmidt, M; Shoeman, R L; Weierstall, U; Westenhoff, S; White, T A; Williams, G J; Yoon, C H; Zatsepin, N; Fromme, P; Duszenko, M; Chapman, H N; Betzel, C.
Afiliación
  • Nass K; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Redecke L; Paul Scherrer Institute (PSI), Forschungstrasse 111, 5232, Villigen, PSI, Switzerland.
  • Perbandt M; Joint Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, and Institute of Biochemistry, University of Lübeck, at Deutsches Elektronen-Synchrotron (DESY), Notkestr. 85, 22607, Hamburg, Germany.
  • Yefanov O; German Centre for Infection Research, University of Lübeck, 23562, Lübeck, Germany.
  • Klinge M; Institute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
  • Koopmann R; Deutsches Elektronen Synchrotron (DESY), Photon Science, Notkestr. 85, 22607, Hamburg, Germany.
  • Stellato F; Institute of Biochemistry and Molecular Biology, University of Hamburg, at Deutsches Elektronen-Synchrotron (DESY), Notkestr. 85, 22607, Hamburg, Germany.
  • Gabdulkhakov A; The Hamburg Centre for Ultrafast Imaging (CUI), Luruper Chaussee 149, 22761, Hamburg, Germany.
  • Schönherr R; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Rehders D; Joint Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, and Institute of Biochemistry, University of Lübeck, at Deutsches Elektronen-Synchrotron (DESY), Notkestr. 85, 22607, Hamburg, Germany.
  • Lahey-Rudolph JM; BioAgilytix Europe GmbH, Lademannbogen 10, 22339, Hamburg, Germany.
  • Aquila A; Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str.4, 72076, Tübingen, Germany.
  • Barty A; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Basu S; Dipartimento di Fisica, Università di Roma Tor Vergata and INFN, Via della Ricerca Scientifica 1, 00133, Rome, Italy.
  • Doak RB; Institute of Protein Research, Russian Academy of Sciences, 4 Institutskaya Str., Pushchino, Moscow Region, Russia, 142290.
  • Duden R; Institute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
  • Frank M; Deutsches Elektronen Synchrotron (DESY), Photon Science, Notkestr. 85, 22607, Hamburg, Germany.
  • Fromme R; Joint Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, and Institute of Biochemistry, University of Lübeck, at Deutsches Elektronen-Synchrotron (DESY), Notkestr. 85, 22607, Hamburg, Germany.
  • Kassemeyer S; BODE Chemie GmbH, Melanchthonstraße 27, 22525, Hamburg, Germany.
  • Katona G; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Kirian R; Institute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
  • Liu H; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Majoul I; LCLS, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA, 94025, USA.
  • Martin-Garcia JM; Center for Free-Electron Laser Science (CFEL), Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Messerschmidt M; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ, 85287-160, USA.
  • Shoeman RL; European Molecular Biology Laboratory (EMBL), Grenoble Outstation, 71 Avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 9, Grenoble, France.
  • Weierstall U; Department of Physics, Arizona State University, Tempe, AZ, 85411, USA.
  • Westenhoff S; Max Planck Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.
  • White TA; Institute of Biology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
  • Williams GJ; Biology and Biotechnology Division, Physical & Life Sciences Directorate, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA, 94550, USA.
  • Yoon CH; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ, 85287-160, USA.
  • Zatsepin N; Max-Planck-Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.
  • Fromme P; Department of Chemistry and Molecular Biology, University of Gothenburg, 40530, Gothenburg, Sweden.
  • Duszenko M; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ, 85287-160, USA.
  • Chapman HN; Department of Physics, Arizona State University, Tempe, AZ, 85411, USA.
  • Betzel C; Complex Systems Division, Beijing Computational Science Research Center, 100193, Beijing, China.
Nat Commun ; 11(1): 620, 2020 01 30.
Article en En | MEDLINE | ID: mdl-32001697
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trypanosoma brucei brucei / Coenzimas / Cristalización / IMP Deshidrogenasa Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trypanosoma brucei brucei / Coenzimas / Cristalización / IMP Deshidrogenasa Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Alemania