Clinical Characteristics and Disease Course in Black Patients With Lymphomatoid Papulosis: A Case Series
J Drugs Dermatol
; 19(1): 89-91, 2020 Jan 01.
Article
en En
| MEDLINE
| ID: mdl-32023015
ABSTRACT
INTRODUCTION:
Lymphomatoid papulosis (LyP) is a CD30+ T-cell lymphoproliferative disorder (LPD) presenting as a recurrent eruption of papules and nodules which resolve spontaneously. CD30+ LPD prevalence in African American (AA)/Black patients is lower compared to White patients. CD30+ LPD has been recently reported to have worse outcomes in AA patients compared to White patients.METHODS:
A retrospective chart review identified eight AA patients with LyP. We describe our experience with these eight patients and review the literature on similar cases.RESULTS:
In half of the eight included patients, lesions occurred 1-4 years before they were diagnosed. In six patients (75%), resolution of the lesions resulted in hyperpigmented macules and scars. Five patients (63%) had also mycosis fungoides. Most of the patients who were followed (4/7, 57%) did not have complete resolution at their last visit, despite different treatment approaches.Discussion:
Our results highlight that although LyP has an indolent course in AA/Black patients, residual hyperpigmentation and scars frequently occur, highlighting the need for better treatments of this lymphoproliferative disorder in this specific population. J Drugs Dermatol. 2020;19(1)89-91. doi10.36849/JDD.2020.4602
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
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Negro o Afroamericano
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Papulosis Linfomatoide
Tipo de estudio:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Drugs Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
2020
Tipo del documento:
Article