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Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.
Di Magno, Laura; Manni, Simona; Di Pastena, Fiorella; Coni, Sonia; Macone, Alberto; Cairoli, Sara; Sambucci, Manolo; Infante, Paola; Moretti, Marta; Petroni, Marialaura; Nicoletti, Carmine; Capalbo, Carlo; De Smaele, Enrico; Di Marcotullio, Lucia; Giannini, Giuseppe; Battistini, Luca; Goffredo, Bianca Maria; Iorio, Egidio; Agostinelli, Enzo; Maroder, Marella; Canettieri, Gianluca.
Afiliación
  • Di Magno L; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161 Rome, Italy.
  • Manni S; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Di Pastena F; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Coni S; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Macone A; Department of Biochemical Sciences A. Rossi Fanelli, Sapienza University of Rome, 00185 Rome, Italy.
  • Cairoli S; Division of Metabolism and Research Unit of metabolic Biochemistry, Children's Hospital and Research Institute Bambino Gesù IRCCS, 00146 Rome, Italy.
  • Sambucci M; IRCCS Santa Lucia Foundation, Neuroimmunology Unit, 00143 Rome, Italy.
  • Infante P; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161 Rome, Italy.
  • Moretti M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Petroni M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Nicoletti C; Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Unit of Histology and Medical Embryology, Sapienza University of Rome, 00161 Rome, Italy.
  • Capalbo C; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • De Smaele E; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Di Marcotullio L; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161 Rome, Italy.
  • Giannini G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Battistini L; IRCCS Santa Lucia Foundation, Neuroimmunology Unit, 00143 Rome, Italy.
  • Goffredo BM; Division of Metabolism and Research Unit of metabolic Biochemistry, Children's Hospital and Research Institute Bambino Gesù IRCCS, 00146 Rome, Italy.
  • Iorio E; Core Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.
  • Agostinelli E; Department of Biochemical Sciences A. Rossi Fanelli, Sapienza University of Rome, 00185 Rome, Italy; International Polyamines Foundation-ONLUS, 00159 Rome, Italy.
  • Maroder M; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
  • Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy; Istituto Pasteur, Fondazione Cenci-Bolognetti, Sapienza University of Rome, 00161 Rome, Italy; International Polyamines Foundation-ONLUS, 00159 Rome, Italy. Electronic address: gianluca.canettieri@uniroma1.it.
Cell Rep ; 30(6): 1735-1752.e7, 2020 02 11.
Article en En | MEDLINE | ID: mdl-32049007
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenformina / Proteínas Hedgehog / Proteínas Co-Represoras / Hipoglucemiantes / Neoplasias / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2020 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenformina / Proteínas Hedgehog / Proteínas Co-Represoras / Hipoglucemiantes / Neoplasias / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2020 Tipo del documento: Article País de afiliación: Italia