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OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Verboom, Lien; Martens, Arne; Priem, Dario; Hoste, Esther; Sze, Mozes; Vikkula, Hanna; Van Hove, Lisette; Voet, Sofie; Roels, Jana; Maelfait, Jonathan; Bongiovanni, Laura; de Bruin, Alain; Scott, Charlotte L; Saeys, Yvan; Pasparakis, Manolis; Bertrand, Mathieu J M; van Loo, Geert.
Afiliación
  • Verboom L; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Martens A; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Priem D; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Hoste E; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Sze M; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Vikkula H; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Van Hove L; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Voet S; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Roels J; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Applied Mathematics, Computer Sciences, and Statistics, Ghent University, 9052 Ghent, Belgium.
  • Maelfait J; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Bongiovanni L; Dutch Molecular Pathology Center, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht 3584, the Netherlands; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen 9713, the Netherlands.
  • de Bruin A; Dutch Molecular Pathology Center, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht 3584, the Netherlands; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen 9713, the Netherlands.
  • Scott CL; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • Saeys Y; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Applied Mathematics, Computer Sciences, and Statistics, Ghent University, 9052 Ghent, Belgium.
  • Pasparakis M; Institute for Genetics, Centre for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.
  • Bertrand MJM; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.
  • van Loo G; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium. Electronic address: geert.vanloo@irc.vib-ugent.be.
Cell Rep ; 30(7): 2237-2247.e6, 2020 02 18.
Article en En | MEDLINE | ID: mdl-32075762
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Carcinoma Hepatocelular / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína de Dominio de Muerte Asociada a Fas / Hepatitis / Neoplasias Hepáticas Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2020 Tipo del documento: Article País de afiliación: Bélgica
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Carcinoma Hepatocelular / Proteína Serina-Treonina Quinasas de Interacción con Receptores / Proteína de Dominio de Muerte Asociada a Fas / Hepatitis / Neoplasias Hepáticas Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2020 Tipo del documento: Article País de afiliación: Bélgica