ANTP-SmacN7 fusion peptide-induced radiosensitization in A549 cells and its potential mechanisms.

Zhang, Rongxin; Sun, Hao; Wang, Hong; Zhang, Wenxue; Geng, Kai; Liu, Qiang; Wang, Ping

Zhang, Rongxin; Sun, Hao; Wang, Hong; Zhang, Wenxue; Geng, Kai; Liu, Qiang; Wang, Ping.

Afiliación

Zhang R; National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Sun H; Radiotherapy Department, Tianjin Medical University General Hospital, Tianjin, China.
Wang H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Radiation Medicine, Tianjin, China.
Zhang W; Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Biomedical Engineering, Geriatric Health Engineering Research Center, Tianjin, China.
Geng K; Radiotherapy Department, Tianjin Medical University General Hospital, Tianjin, China.
Liu Q; Radiotherapy Department, Tianjin Medical University General Hospital, Tianjin, China.
Wang P; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Radiation Medicine, Tianjin, China.

Thorac Cancer ; 11(5): 1271-1279, 2020 05.

Article en En | MEDLINE | ID: mdl-32155687

Asunto(s)

Proteína con Homeodominio Antennapedia/química; Neoplasias Pulmonares/radioterapia; Oligopéptidos/química; Fragmentos de Péptidos/farmacología; Fármacos Sensibilizantes a Radiaciones/farmacología; Apoptosis; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; Caspasa 3/genética; Caspasa 3/metabolismo; Caspasa 8/genética; Caspasa 8/metabolismo; Caspasa 9/genética; Caspasa 9/metabolismo; Rayos gamma; Humanos; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; Células Tumorales Cultivadas

Palabras clave

A549 cell line; apoptosiscaspase activationradiation sensitizationSmac

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligopéptidos / Fragmentos de Péptidos / Fármacos Sensibilizantes a Radiaciones / Proteína con Homeodominio Antennapedia / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Thorac Cancer Año: 2020 Tipo del documento: Article País de afiliación: China

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