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Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia.
Winn, Blake A; Devkota, Laxman; Kuch, Bunnarack; MacDonough, Matthew T; Strecker, Tracy E; Wang, Yifan; Shi, Zhe; Gerberich, Jeni L; Mondal, Deboprosad; Ramirez, Alejandro J; Hamel, Ernest; Chaplin, David J; Davis, Peter; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G.
Afiliación
  • Winn BA; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Devkota L; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Kuch B; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • MacDonough MT; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Wang Y; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Shi Z; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Gerberich JL; Predictive Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States.
  • Mondal D; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Ramirez AJ; Mass Spectrometry Center, Baylor University, One Bear Place #97046, Waco, Texas 76798-7046, United States.
  • Hamel E; Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, Maryland 21702, United States.
  • Chaplin DJ; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
  • Davis P; Fast Biopharma Ltd., 10 Aston Park, Aston Rowant, OX49 5SW, United Kingdom.
  • Mason RP; Fast Biopharma Ltd., 10 Aston Park, Aston Rowant, OX49 5SW, United Kingdom.
  • Trawick ML; Predictive Imaging Research Laboratory, Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9058, United States.
  • Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, Texas 76798-7348, United States.
J Nat Prod ; 83(4): 937-954, 2020 04 24.
Article en En | MEDLINE | ID: mdl-32196334
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estilbenos / Profármacos / Antineoplásicos Fitogénicos Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Nat Prod Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estilbenos / Profármacos / Antineoplásicos Fitogénicos Tipo de estudio: Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Revista: J Nat Prod Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos