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First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors.
Okano, Naohiro; Naruge, Daisuke; Kawai, Kirio; Kobayashi, Takaaki; Nagashima, Fumio; Endou, Hitoshi; Furuse, Junji.
Afiliación
  • Okano N; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan. naohiro-okano@ks.kyorin-u.ac.jp.
  • Naruge D; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
  • Kawai K; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
  • Kobayashi T; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
  • Nagashima F; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
  • Endou H; J-Pharma Co., Ltd., Yokohama, Kanagawa, Japan.
  • Furuse J; Department of Medical Oncology, Kyorin University Faculty of Medicine, 6-20-2, Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
Invest New Drugs ; 38(5): 1495-1506, 2020 10.
Article en En | MEDLINE | ID: mdl-32198649
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tirosina / Benzoxazoles / Transportador de Aminoácidos Neutros Grandes 1 / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2020 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tirosina / Benzoxazoles / Transportador de Aminoácidos Neutros Grandes 1 / Neoplasias / Antineoplásicos Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2020 Tipo del documento: Article País de afiliación: Japón