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High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics.
Gérard, Annabelle; Woolfe, Adam; Mottet, Guillaume; Reichen, Marcel; Castrillon, Carlos; Menrath, Vera; Ellouze, Sami; Poitou, Adeline; Doineau, Raphaël; Briseno-Roa, Luis; Canales-Herrerias, Pablo; Mary, Pascaline; Rose, Gregory; Ortega, Charina; Delincé, Matthieu; Essono, Sosthene; Jia, Bin; Iannascoli, Bruno; Richard-Le Goff, Odile; Kumar, Roshan; Stewart, Samantha N; Pousse, Yannick; Shen, Bingqing; Grosselin, Kevin; Saudemont, Baptiste; Sautel-Caillé, Antoine; Godina, Alexei; McNamara, Scott; Eyer, Klaus; Millot, Gaël A; Baudry, Jean; England, Patrick; Nizak, Clément; Jensen, Allan; Griffiths, Andrew D; Bruhns, Pierre; Brenan, Colin.
Afiliación
  • Gérard A; HiFiBiO Therapeutics SAS, Paris, France.
  • Woolfe A; HiFiBiO Therapeutics SAS, Paris, France.
  • Mottet G; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • Reichen M; HiFiBiO Therapeutics SAS, Paris, France.
  • Castrillon C; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • Menrath V; École Doctorale Frontières du Vivant (FdV), Centre de Recherches Interdisciplinaires, Paris, France.
  • Ellouze S; Laboratoire de Biochimie (LBC), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
  • Poitou A; HiFiBiO Therapeutics SAS, Paris, France.
  • Doineau R; HiFiBiO Therapeutics SAS, Paris, France.
  • Briseno-Roa L; HiFiBiO Therapeutics SAS, Paris, France.
  • Canales-Herrerias P; HiFiBiO Therapeutics SAS, Paris, France.
  • Mary P; École Doctorale Frontières du Vivant (FdV), Centre de Recherches Interdisciplinaires, Paris, France.
  • Rose G; Laboratoire de Biochimie (LBC), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
  • Ortega C; Institute for Integrative Nanosciences, Leibniz IFW Dresden e.V., Dresden, Germany.
  • Delincé M; HiFiBiO Therapeutics SAS, Paris, France.
  • Essono S; Medetia Pharma, Institut Imagine, Paris, France.
  • Jia B; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • Iannascoli B; École Doctorale Frontières du Vivant (FdV), Centre de Recherches Interdisciplinaires, Paris, France.
  • Richard-Le Goff O; Laboratoire Colloïdes et Matériaux Divisés (LCMD), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
  • Kumar R; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Stewart SN; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Pousse Y; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Shen B; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Grosselin K; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Saudemont B; Pfizer, Cambridge, MA, USA.
  • Sautel-Caillé A; Abbvie Bioresearch Center, Worcester, MA, USA.
  • Godina A; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • McNamara S; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • Eyer K; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Millot GA; HiFiBiO Therapeutics Inc., Cambridge, MA, USA.
  • Baudry J; HiFiBiO Therapeutics SAS, Paris, France.
  • England P; HiFiBiO Therapeutics SAS, Paris, France.
  • Nizak C; HiFiBiO Therapeutics SAS, Paris, France.
  • Jensen A; Laboratoire de Biochimie (LBC), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
  • Griffiths AD; Unit of Antibodies in Therapy and Pathology, Institut Pasteur, UMR1222 INSERM, Paris, France.
  • Bruhns P; Laboratoire de Biochimie (LBC), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
  • Brenan C; Laboratoire de Biochimie (LBC), ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
Nat Biotechnol ; 38(6): 715-721, 2020 06.
Article en En | MEDLINE | ID: mdl-32231335
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Técnicas Analíticas Microfluídicas / Análisis de la Célula Individual / Secuenciación de Nucleótidos de Alto Rendimiento / Anticuerpos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Francia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Técnicas Analíticas Microfluídicas / Análisis de la Célula Individual / Secuenciación de Nucleótidos de Alto Rendimiento / Anticuerpos Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Francia