MicroRNA­431 inhibits the expression of surfactant proteins through the BMP4/activin/TGF­ß signaling pathway by targeting SMAD4.

Shen, Yan-Qing; Bao, Zhi-Dan; Pan, Jing-Jing; Mao, Xiao-Nan; Cheng, Rui; Zhou, Xiao-Guang; Zhou, Xiao-Yu; Yang, Yang

MicroRNA431 inhibits the expression of surfactant proteins through the BMP4/activin/TGFß signaling pathway by targeting SMAD4.

Shen, Yan-Qing; Bao, Zhi-Dan; Pan, Jing-Jing; Mao, Xiao-Nan; Cheng, Rui; Zhou, Xiao-Guang; Zhou, Xiao-Yu; Yang, Yang.

Afiliación

Shen YQ; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Bao ZD; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Pan JJ; Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Mao XN; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Cheng R; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Zhou XG; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Zhou XY; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Yang Y; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.

Int J Mol Med ; 45(5): 1571-1582, 2020 May.

Article en En | MEDLINE | ID: mdl-32323744

Asunto(s)

Activinas/genética; Proteína Morfogenética Ósea 4/genética; MicroARNs/genética; Proteínas Asociadas a Surfactante Pulmonar/genética; Transducción de Señal/genética; Proteína Smad4/genética; Factor de Crecimiento Transformador beta/genética; Células A549; Línea Celular Tumoral; Regulación hacia Abajo/genética; Regulación de la Expresión Génica/genética; Humanos; Pulmón/metabolismo; ARN Mensajero/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Factor de Crecimiento Transformador beta / Activinas / Proteínas Asociadas a Surfactante Pulmonar / MicroARNs / Proteína Smad4 / Proteína Morfogenética Ósea 4 Límite: Humans Idioma: En Revista: Int J Mol Med Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2020 Tipo del documento: Article

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