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A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.
Warnasooriya, Chandani; Feeney, Callen F; Laird, Kholiswa M; Ermolenko, Dmitri N; Kielkopf, Clara L.
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  • Warnasooriya C; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Feeney CF; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Laird KM; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Ermolenko DN; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Kielkopf CL; Department of Biochemistry and Biophysics and Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
Nucleic Acids Res ; 48(10): 5695-5709, 2020 06 04.
Article en En | MEDLINE | ID: mdl-32343311
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndromes Mielodisplásicos / Empalme del ARN / Sitios de Empalme de ARN / Factor de Empalme U2AF / Mutación Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Síndromes Mielodisplásicos / Empalme del ARN / Sitios de Empalme de ARN / Factor de Empalme U2AF / Mutación Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos