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EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
León, Theresa E; Rapoz-D'Silva, Tanya; Bertoli, Cosetta; Rahman, Sunniyat; Magnussen, Michael; Philip, Brian; Farah, Nadine; Richardson, Simon E; Ahrabi, Sara; Guerra-Assunção, José Afonso; Gupta, Rajeev; Nacheva, Elisabeth P; Henderson, Stephen; Herrero, Javier; Linch, David C; de Bruin, Robertus A M; Mansour, Marc R.
Afiliación
  • León TE; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Rapoz-D'Silva T; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Bertoli C; MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
  • Rahman S; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Magnussen M; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Philip B; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Farah N; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Richardson SE; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Ahrabi S; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • Guerra-Assunção JA; Bill Lyons Informatics Centre, UCL Cancer Institute, University College London, London, United Kingdom.
  • Gupta R; Stem Cell Laboratory, UCL Cancer Institute, University College London, London, United Kingdom.
  • Nacheva EP; Health Service Laboratories LLP, UCL Cancer Institute, London, United Kingdom.
  • Henderson S; Bill Lyons Informatics Centre, UCL Cancer Institute, University College London, London, United Kingdom.
  • Herrero J; Bill Lyons Informatics Centre, UCL Cancer Institute, University College London, London, United Kingdom.
  • Linch DC; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom.
  • de Bruin RAM; MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
  • Mansour MR; Department of Haematology, UCL Cancer Institute, University College London, London, United Kingdom. m.mansour@ucl.ac.uk.
Cancer Discov ; 10(7): 998-1017, 2020 07.
Article en En | MEDLINE | ID: mdl-32349972
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Potenciadora del Homólogo Zeste 2 / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Potenciadora del Homólogo Zeste 2 / Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1) Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cancer Discov Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido