Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.

Hornigold, Nick; Dunn, Karen R; Craven, Rachel A; Zougman, Alexandre; Trainor, Sebastian; Shreeve, Rebecca; Brown, Joanne; Sewell, Helen; Shires, Michael; Knowles, Margaret; Fukuwatari, Tsutomu; Maher, Eamonn R; Burns, Julie; Bhattarai, Selina; Menon, Mini; Brazma, Alvis; Scelo, Ghislaine; Feulner, Lara; Riazalhosseini, Yasser; Lathrop, Mark; Harris, Adrian; Selby, Peter J; Banks, Rosamonde E; Vasudev, Naveen S

Hornigold, Nick; Dunn, Karen R; Craven, Rachel A; Zougman, Alexandre; Trainor, Sebastian; Shreeve, Rebecca; Brown, Joanne; Sewell, Helen; Shires, Michael; Knowles, Margaret; Fukuwatari, Tsutomu; Maher, Eamonn R; Burns, Julie; Bhattarai, Selina; Menon, Mini; Brazma, Alvis; Scelo, Ghislaine; Feulner, Lara; Riazalhosseini, Yasser; Lathrop, Mark; Harris, Adrian; Selby, Peter J; Banks, Rosamonde E; Vasudev, Naveen S.

Afiliación

Hornigold N; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Dunn KR; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Craven RA; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Zougman A; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Trainor S; Leeds Institute of Medical Research at St James's, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Shreeve R; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Brown J; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Sewell H; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Shires M; Leeds Institute of Medical Research at St James's, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Knowles M; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Fukuwatari T; Leeds Institute of Medical Research at St James's, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Maher ER; Molecular Genetics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Burns J; Department of Nutrition, The University of Shiga Prefecture, 2500 Hassaka, Hikone, 5228533, Japan.
Bhattarai S; Department of Medical Genetics, University of Cambridge and NIHR Cambridge Biomedical Research Centre, and Cancer Research UK Cambridge Centre, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
Menon M; Molecular Genetics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Brazma A; Department of Pathology, St James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Scelo G; Department of Pathology, St James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.
Feulner L; European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, UK.
Riazalhosseini Y; International Agency for Research on Cancer (IARC), Genetic Epidemiology Group, 150 cours Albert Thomas, 69372, Lyon, France.
Lathrop M; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada.
Harris A; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada.
Selby PJ; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC, H3A 0G1, Canada.
Banks RE; Cancer Research UK Clinical Centre, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK.
Vasudev NS; Clinical and Biomedical Proteomics Group, University of Leeds, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, UK.

Br J Cancer ; 123(1): 137-147, 2020 07.

Article en En | MEDLINE | ID: mdl-32390008

Asunto(s)

3-Hidroxiantranilato 3,4-Dioxigenasa/genética; Carcinoma de Células Renales/genética; Citocinas/genética; Quinurenina 3-Monooxigenasa/genética; Quinurenina/genética; Nicotinamida Fosforribosiltransferasa/genética; Carcinoma de Células Renales/inmunología; Carcinoma de Células Renales/patología; Línea Celular Tumoral; Perfilación de la Expresión Génica; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Quinurenina/metabolismo; Redes y Vías Metabólicas/genética; Proteómica; Escape del Tumor/genética; Escape del Tumor/inmunología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Citocinas / 3-Hidroxiantranilato 3,4-Dioxigenasa / Quinurenina 3-Monooxigenasa / Nicotinamida Fosforribosiltransferasa / Quinurenina Tipo de estudio: Guideline / Prognostic_studies Límite: Humans Idioma: En Revista: Br J Cancer Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

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