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MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation.
Arai, Seiji; Varkaris, Andreas; Nouri, Mannan; Chen, Sen; Xie, Lisha; Balk, Steven P.
Afiliación
  • Arai S; Hematology-Oncology Division, Department of Medicine, and Cancer Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States.
  • Varkaris A; Department of Urology, Gunma University Hospital, Maebashi, Japan.
  • Nouri M; Hematology-Oncology Division, Department of Medicine, and Cancer Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States.
  • Chen S; Hematology-Oncology Division, Department of Medicine, and Cancer Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States.
  • Xie L; Hematology-Oncology Division, Department of Medicine, and Cancer Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States.
  • Balk SP; Hematology-Oncology Division, Department of Medicine, and Cancer Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, United States.
Elife ; 92020 06 02.
Article en En | MEDLINE | ID: mdl-32484436
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-bcl-2 / Ubiquitina-Proteína Ligasas / Inhibidores de Proteínas Quinasas / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Proteínas de la Membrana / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas c-bcl-2 / Ubiquitina-Proteína Ligasas / Inhibidores de Proteínas Quinasas / Proteína 1 de la Secuencia de Leucemia de Células Mieloides / Proteínas de la Membrana / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos