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Safety and Efficacy of 48 and 96 Weeks of Alendronate in Children and Adolescents With Perinatal Human Immunodeficiency Virus Infection and Low Bone Mineral Density for Age.
Lindsey, Jane C; Jacobson, Denise L; Spiegel, Hans M; Gordon, Catherine M; Hazra, Rohan; Siberry, George K.
Afiliación
  • Lindsey JC; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Jacobson DL; Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Spiegel HM; Kelly Government Solutions, Contractor to National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA.
  • Gordon CM; Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Hazra R; Maternal and Pediatric Infectious Diseases Branch, Division of Extramural Research, Eunice Kennedy Shriver National Institute of Child Health and Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA.
  • Siberry GK; Office of HIV/AIDS, US Agency for International Development, Washington, D.C., USA.
Clin Infect Dis ; 72(6): 1059-1063, 2021 03 15.
Article en En | MEDLINE | ID: mdl-32584996
No safety concerns were identified in a randomized, crossover study of alendronate/placebo in youth with perinatal HIV infection and low bone mineral density (BMD). BMD improved with 48 weeks of alendronate and continued to improve with an additional 48 weeks of therapy. Gains were largely maintained 48 weeks after stopping alendronate.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Óseas Metabólicas / Infecciones por VIH / Conservadores de la Densidad Ósea Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Óseas Metabólicas / Infecciones por VIH / Conservadores de la Densidad Ósea Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos