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Recycling of Precolectomy Anti-Tumor Necrosis Factor Agents in Chronic Pouch Inflammation Is Associated With Treatment Failure.
Kayal, Maia; Lambin, Thomas; Plietz, Michael; Rizvi, Anam; Radcliffe, Marlana; Khaitov, Sergey; Sylla, Patricia; Greenstein, Alexander J; Colombel, Jean Frederic; Dubinsky, Marla C; Ungaro, Ryan C.
Afiliación
  • Kayal M; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: maia.kayal@mountsinai.org.
  • Lambin T; Division of Gastroenterology, Lille University Hospital, Lille, France.
  • Plietz M; Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Rizvi A; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Radcliffe M; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Khaitov S; Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Sylla P; Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Greenstein AJ; Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Colombel JF; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Dubinsky MC; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Ungaro RC; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Clin Gastroenterol Hepatol ; 19(7): 1491-1493.e3, 2021 07.
Article en En | MEDLINE | ID: mdl-32668342
ABSTRACT
Despite improvements in medical management, 10%-15% of patients with ulcerative colitis (UC) require total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) for refractory disease.1 Acute pouchitis is the most common post-IPAA inflammatory condition, with cumulative incidence of 45% at 5 years.2 Up to 20%-30% of patients develop chronic pouch inflammation (CPI), categorized as antibiotic responsive, antibiotic refractory, or Crohn's disease-like (CDL).3.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Proctocolectomía Restauradora / Reservoritis / Reservorios Cólicos Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Gastroenterol Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Proctocolectomía Restauradora / Reservoritis / Reservorios Cólicos Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Gastroenterol Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article