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Differential MHC-II expression and phagocytic functions of embryo-derived cardiac macrophages in the course of myocardial infarction in mice.
Weinberger, Tobias; Räuber, Saskia; Schneider, Vanessa; Messerer, Denise; Fischer, Maximilian; Rudi, Wolf-Stephan; Kobayashi, Yasuhiro; Schulz, Christian.
Afiliación
  • Weinberger T; Medizinische Klinik und Poliklinik I, Klinikum der Universität, Ludwig-Maximilians-Universität, Munich, Germany.
  • Räuber S; Walter-Brendel-Center for Experimental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.
  • Schneider V; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
  • Messerer D; Medizinische Klinik und Poliklinik I, Klinikum der Universität, Ludwig-Maximilians-Universität, Munich, Germany.
  • Fischer M; Walter-Brendel-Center for Experimental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.
  • Rudi WS; Medizinische Klinik und Poliklinik I, Klinikum der Universität, Ludwig-Maximilians-Universität, Munich, Germany.
  • Kobayashi Y; Walter-Brendel-Center for Experimental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.
  • Schulz C; Medizinische Klinik und Poliklinik I, Klinikum der Universität, Ludwig-Maximilians-Universität, Munich, Germany.
Eur J Immunol ; 51(1): 250-252, 2021 01.
Article en En | MEDLINE | ID: mdl-32761616
ABSTRACT
In mouse myocardial infarction, we combined lineage tracing of cardiac macrophages, mapping their ontogeny, with an analysis of their phenotype and phagocytic functions. While embryo-derived macrophages were most abundant in homeostasis, bone marrow-derived MHC-IIlo macrophages increased in both numbers and phagocytic capacity to clear necrotic cardiomyocytes early after ischemia/perfusion injury.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos de Histocompatibilidad Clase II / Macrófagos / Infarto del Miocardio / Miocardio Límite: Animals Idioma: En Revista: Eur J Immunol Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos de Histocompatibilidad Clase II / Macrófagos / Infarto del Miocardio / Miocardio Límite: Animals Idioma: En Revista: Eur J Immunol Año: 2021 Tipo del documento: Article País de afiliación: Alemania