Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO-1/NF-&#954;B signaling pathway.

Zhang, Yang; Zhu, Xiao-Bo; Zhao, Jin-Chuan; Gao, Xian-Feng; Zhang, Xiao-Na; Hou, Kun

Neuroprotective effect of resveratrol against radiation after surgically induced brain injury by reducing oxidative stress, inflammation, and apoptosis through NRf2/HO-1/NF-κB signaling pathway.

Zhang, Yang; Zhu, Xiao-Bo; Zhao, Jin-Chuan; Gao, Xian-Feng; Zhang, Xiao-Na; Hou, Kun.

Afiliación

Zhang Y; Department of Neurosurgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Zhu XB; Department of Neurosurgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Zhao JC; Department of Neurosurgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Gao XF; Department of Neurosurgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Zhang XN; Department of Anesthesiology, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Hou K; Department of Neurosurgery, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.

J Biochem Mol Toxicol ; 34(12): e22600, 2020 Dec.

Article en En | MEDLINE | ID: mdl-32815255

Asunto(s)

Apoptosis/efectos de los fármacos; Lesiones Encefálicas/etiología; Fármacos Neuroprotectores/farmacología; Estrés Oxidativo/efectos de los fármacos; Resveratrol/farmacología; Transducción de Señal/efectos de los fármacos; Animales; Lesiones Encefálicas/metabolismo; Hemo Oxigenasa (Desciclizante)/metabolismo; Masculino; Factor 2 Relacionado con NF-E2/metabolismo; FN-kappa B/metabolismo; Ratas; Ratas Wistar

Palabras clave

Bcl-2; NF-κB; Nrf2; caspase-3; neurosurgery; radiation; resveratrol

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Lesiones Encefálicas / Transducción de Señal / Apoptosis / Estrés Oxidativo / Fármacos Neuroprotectores / Resveratrol Límite: Animals Idioma: En Revista: J Biochem Mol Toxicol Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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