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Serum concentration of the CKD4/6 inhibitor abemaciclib, but not of creatinine, strongly predicts hematological adverse events in patients with breast cancer: a preliminary report.
Maeda, Akimitsu; Irie, Kei; Hashimoto, Naoya; Fukushima, Shoji; Ando, Hitoshi; Okada, Akira; Ebi, Hiromichi; Kajita, Masaki; Iwata, Hiroji; Sawaki, Masataka.
Afiliación
  • Maeda A; Department of Pharmacy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Aichi, Nagoya, 464-8681, Japan. m.akimitsu@aichi-cc.jp.
  • Irie K; Department of Pharmaceutics, Faculty of Pharmaceutical Science, Kobe Gakuin University, 1-1-3 Minatojima, Kobe, Chuo-ku, 650-8586, Japan.
  • Hashimoto N; Department of Pharmacy, Kobe City Hospital Organization, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-minami-machi, Kobe, Chuo-ku, 650-0047, Japan.
  • Fukushima S; Department of Pharmacy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Aichi, Nagoya, 464-8681, Japan.
  • Ando H; Department of Pharmaceutics, Faculty of Pharmaceutical Science, Kobe Gakuin University, 1-1-3 Minatojima, Kobe, Chuo-ku, 650-8586, Japan.
  • Okada A; Department of Cellular and Molecular Function Analysis, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
  • Ebi H; Department of Regulatory Science, Faculty of Pharmacy, Musashino University, 1-1-20 Shinmachi , Nishitokyo City, 202-8585, Japan.
  • Kajita M; Division of Molecular Therapeutics, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, 464-8681, Nagoya, Aichi, Japan.
  • Iwata H; Department of Pharmacy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Aichi, Nagoya, 464-8681, Japan.
  • Sawaki M; Department of Breast Oncology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan.
Invest New Drugs ; 39(1): 272-277, 2021 02.
Article en En | MEDLINE | ID: mdl-32856274
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bencimidazoles / Neoplasias de la Mama / Quinasa 4 Dependiente de la Ciclina / Quinasa 6 Dependiente de la Ciclina / Aminopiridinas / Enfermedades Hematológicas / Antineoplásicos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bencimidazoles / Neoplasias de la Mama / Quinasa 4 Dependiente de la Ciclina / Quinasa 6 Dependiente de la Ciclina / Aminopiridinas / Enfermedades Hematológicas / Antineoplásicos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: Japón