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Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo.
Maldini, Colby R; Claiborne, Daniel T; Okawa, Ken; Chen, Tao; Dopkin, Derrick L; Shan, Xiaochuan; Power, Karen A; Trifonova, Radiana T; Krupp, Katharine; Phelps, Meredith; Vrbanac, Vladimir D; Tanno, Serah; Bateson, Timothy; Leslie, George J; Hoxie, James A; Boutwell, Christian L; Riley, James L; Allen, Todd M.
Afiliación
  • Maldini CR; Department of Microbiology, Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Claiborne DT; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Okawa K; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Chen T; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Dopkin DL; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Shan X; Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Power KA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Trifonova RT; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Krupp K; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Phelps M; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Vrbanac VD; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Tanno S; Human Immune System Mouse Program, Massachusetts General Hospital, Boston, MA, USA.
  • Bateson T; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Leslie GJ; Human Immune System Mouse Program, Massachusetts General Hospital, Boston, MA, USA.
  • Hoxie JA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Boutwell CL; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Riley JL; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Allen TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Nat Med ; 26(11): 1776-1787, 2020 11.
Article en En | MEDLINE | ID: mdl-32868878
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos CD4 / Infecciones por VIH / Inmunoterapia Adoptiva / Receptores Quiméricos de Antígenos Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antígenos CD4 / Infecciones por VIH / Inmunoterapia Adoptiva / Receptores Quiméricos de Antígenos Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos