Nontoxic-dose deoxynivalenol aggravates lipopolysaccharides-induced inflammation and tight junction disorder in IPEC-J2 cells through activation of NF-&#954;B and LC3B.

Ge, Lei; Lin, Ziman; Le, Guannan; Hou, Lili; Mao, Xinru; Liu, Shuiping; Liu, Dandan; Gan, Fang; Huang, Kehe

Nontoxic-dose deoxynivalenol aggravates lipopolysaccharides-induced inflammation and tight junction disorder in IPEC-J2 cells through activation of NF-κB and LC3B.

Ge, Lei; Lin, Ziman; Le, Guannan; Hou, Lili; Mao, Xinru; Liu, Shuiping; Liu, Dandan; Gan, Fang; Huang, Kehe.

Afiliación

Ge L; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Lin Z; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Le G; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Hou L; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Mao X; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Liu S; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Liu D; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Gan F; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor
Huang K; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Labor

Food Chem Toxicol ; 145: 111712, 2020 Nov.

Article en En | MEDLINE | ID: mdl-32877744

Asunto(s)

Inflamación/inmunología; Proteínas Asociadas a Microtúbulos/inmunología; FN-kappa B/inmunología; Uniones Estrechas/efectos de los fármacos; Tricotecenos/toxicidad; Animales; Línea Celular; Células Epiteliales/efectos de los fármacos; Células Epiteliales/inmunología; Inflamación/etiología; Inflamación/genética; Mucosa Intestinal/efectos de los fármacos; Mucosa Intestinal/inmunología; Lipopolisacáridos/efectos adversos; Proteínas Asociadas a Microtúbulos/genética; FN-kappa B/genética; Proteína con Dominio Pirina 3 de la Familia NLR/genética; Proteína con Dominio Pirina 3 de la Familia NLR/inmunología; Transducción de Señal/efectos de los fármacos; Uniones Estrechas/inmunología

Palabras clave

Deoxynivalenol; Inflammation; LC3B; LPS; NF-κB signaling pathway; Tight junction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tricotecenos / FN-kappa B / Uniones Estrechas / Inflamación / Proteínas Asociadas a Microtúbulos Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Food Chem Toxicol Año: 2020 Tipo del documento: Article

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