Candida albicans and candidalysin in inflammatory disorders and cancer.
Immunology
; 162(1): 11-16, 2021 01.
Article
en En
| MEDLINE
| ID: mdl-32880925
ABSTRACT
As our understanding of mycology progresses, the impact of fungal microbes on human health has become increasingly evident. Candida albicans is a common commensal fungus that gives rise to local and systemic infections, particularly in immunocompromised patients where it can result in mortality. However, C. albicans has also been quietly linked with a variety of inflammatory disorders, to which it has traditionally been considered incidental; recent studies may now provide new aspects of these relationships for further consideration. This review provides a novel perspective on the impact of C. albicans and its peptide toxin, candidalysin, on human health, exploring their contributions to pathology within a variety of diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Candida albicans
/
Proteínas Fúngicas
/
Inflamación
/
Neoplasias
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Immunology
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido