8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway.

Ding, Hong-Yue; Yang, Wan-Yong; Zhang, Li-Hong; Li, Li; Xie, Feng; Li, Hua-Yi; Chen, Xiao-Yu; Tu, Zeng; Li, Yi; Chen, Yong; Yang, Sheng-Yong

Ding, Hong-Yue; Yang, Wan-Yong; Zhang, Li-Hong; Li, Li; Xie, Feng; Li, Hua-Yi; Chen, Xiao-Yu; Tu, Zeng; Li, Yi; Chen, Yong; Yang, Sheng-Yong.

Afiliación

Ding HY; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Yang WY; Dongguan Waterfront Zone Central Hospital, Dongguan, Guangdong, China.
Zhang LH; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Li L; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Xie F; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Li HY; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Chen XY; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Tu Z; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Li Y; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Chen Y; Department of Radiology and Intervention, The General Hospital of Ningxia Medical University, Yinchuan, China.
Yang SY; Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.

Cell Transplant ; 29: 963689720958656, 2020.

Article en En | MEDLINE | ID: mdl-32907379

Asunto(s)

2-Cloroadenosina/análogos & derivados; Adenosina Desaminasa/metabolismo; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Proteínas de Unión al ARN/metabolismo; Transducción de Señal; Proteína p53 Supresora de Tumor/metabolismo; 2-Cloroadenosina/farmacología; Adenosina Desaminasa/química; Apoptosis/efectos de los fármacos; Puntos de Control del Ciclo Celular/efectos de los fármacos; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Ciclina D1/metabolismo; Inhibidor p21 de las Quinasas Dependientes de la Ciclina/metabolismo; Regulación hacia Abajo/efectos de los fármacos; Femenino; Humanos; Dominios Proteicos; Proteínas de Unión al ARN/química; Transducción de Señal/efectos de los fármacos

Palabras clave

8-Cl-Ado; ADAR1; breast cancer cells; cell cycle; double-stranded RNA-binding domain

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Transducción de Señal / 2-Cloroadenosina / Adenosina Desaminasa / Proteína p53 Supresora de Tumor / Proteínas de Unión al ARN Límite: Female / Humans Idioma: En Revista: Cell Transplant Asunto de la revista: TRANSPLANTE Año: 2020 Tipo del documento: Article País de afiliación: China

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