Pseudogene AKR1B10P1 enhances tumorigenicity and regulates epithelial-mesenchymal transition in hepatocellular carcinoma via stabilizing SOX4.

Hao, Fengjie; Fei, Xiaochun; Ren, Xinping; Xi Xiao, Joanna; Chen, Yongjun; Wang, Junqing

Hao, Fengjie; Fei, Xiaochun; Ren, Xinping; Xi Xiao, Joanna; Chen, Yongjun; Wang, Junqing.

Afiliación

Hao F; Department of General Surgery, Hepatobiliary Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Fei X; Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Ren X; Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Xi Xiao J; Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Chen Y; Department of General Surgery, Hepatobiliary Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Wang J; Department of General Surgery, Hepatobiliary Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

J Cell Mol Med ; 24(20): 11779-11790, 2020 10.

Article en En | MEDLINE | ID: mdl-32924268

Asunto(s)

Carcinogénesis/genética; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/patología; Transición Epitelial-Mesenquimal/genética; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; Seudogenes; Factores de Transcripción SOXC/metabolismo; Animales; Apoptosis/genética; Secuencia de Bases; Ciclo Celular/genética; Línea Celular Tumoral; Movimiento Celular/genética; Proliferación Celular/genética; Humanos; Masculino; Ratones Endogámicos BALB C; Ratones Desnudos; MicroARNs/genética; MicroARNs/metabolismo; Persona de Mediana Edad; Estabilidad Proteica; ARN Mensajero/genética; ARN Mensajero/metabolismo; Transcripción Genética

Palabras clave

AKR1B10P1; SOX4; hepatocellular carcinoma; metastasis; miR-138

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Seudogenes / Carcinoma Hepatocelular / Factores de Transcripción SOXC / Transición Epitelial-Mesenquimal / Carcinogénesis / Neoplasias Hepáticas Límite: Animals / Humans / Male / Middle aged Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article

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