Evaluation of a Competitive Equilibrium Dialysis Approach for Assessing the Impact of Protein Binding on Clearance Predictions.

Jones, Robert S; Chang, Jae H; Flores, Mauricio; Brecht, Elliot

Jones, Robert S; Chang, Jae H; Flores, Mauricio; Brecht, Elliot.

Afiliación

Jones RS; Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080. Electronic address: jones.robert@gene.com.
Chang JH; Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080.
Flores M; Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080.
Brecht E; Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080.

J Pharm Sci ; 110(1): 536-542, 2021 01.

Article en En | MEDLINE | ID: mdl-32941852

Asunto(s)

Plasma; Diálisis Renal; Cinética; Tasa de Depuración Metabólica; Unión Proteica

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plasma / Diálisis Renal Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Pharm Sci Año: 2021 Tipo del documento: Article

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