Protein signatures from blood plasma and urine suggest changes in vascular function and IL-12 signaling in elderly with a history of chronic diseases compared with an age-matched healthy cohort.

Yu, Yanbao; Singh, Harinder; Kwon, Keehwan; Tsitrin, Tamara; Petrini, Joann; Nelson, Karen E; Pieper, Rembert

Yu, Yanbao; Singh, Harinder; Kwon, Keehwan; Tsitrin, Tamara; Petrini, Joann; Nelson, Karen E; Pieper, Rembert.

Afiliación

Yu Y; J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD, 20850, USA.
Singh H; J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD, 20850, USA.
Kwon K; J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD, 20850, USA.
Tsitrin T; J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD, 20850, USA.
Petrini J; Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT, 06810, USA.
Nelson KE; J. Craig Venter Institute, 9605 Medical Center Drive, Rockville, MD, 20850, USA.
Pieper R; J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, CA, 92037, USA.

Geroscience ; 43(2): 593-606, 2021 04.

Article en En | MEDLINE | ID: mdl-32974878

Asunto(s)

Envejecimiento Saludable; Interleucina-12; Anciano; Anciano de 80 o más Años; Enfermedad Crónica; Humanos; Plasma; Transducción de Señal

Palabras clave

Afamin; Cathepsin D; Chronic disease; Healthy aging; IL-12 signaling; Inflammaging; Interleukin 12; Metabolic syndrome; Proinflammatory cytokines; Proteomics; Senescence; Urinary proteome; Vasculature

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Interleucina-12 / Envejecimiento Saludable Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans Idioma: En Revista: Geroscience Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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