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STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition.
Sitthideatphaiboon, Piyada; Galan-Cobo, Ana; Negrao, Marcelo V; Qu, Xiao; Poteete, Alissa; Zhang, Fahao; Liu, Diane D; Lewis, Whitney E; Kemp, Haley N; Lewis, Jeff; Rinsurongkawong, Waree; Giri, Uma; Lee, J Jack; Zhang, Jianjun; Roth, Jack A; Swisher, Stephen; Heymach, John V.
Afiliación
  • Sitthideatphaiboon P; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Galan-Cobo A; Division of Medical Oncology, Department of Medicine, Faculty of Medicine, Chulalongkorn University/King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
  • Negrao MV; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Qu X; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Poteete A; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Zhang F; Institute of Oncology, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, P.R. China.
  • Liu DD; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lewis WE; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kemp HN; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lewis J; Division of Pharmacy, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rinsurongkawong W; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Giri U; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lee JJ; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Zhang J; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Roth JA; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Swisher S; Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Heymach JV; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Clin Cancer Res ; 27(6): 1720-1733, 2021 03 15.
Article en En | MEDLINE | ID: mdl-33323404
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Carcinoma de Pulmón de Células no Pequeñas / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Quinasas de la Proteína-Quinasa Activada por el AMP / Glutaminasa / Neoplasias Pulmonares / Mutación Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Carcinoma de Pulmón de Células no Pequeñas / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Quinasas de la Proteína-Quinasa Activada por el AMP / Glutaminasa / Neoplasias Pulmonares / Mutación Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article