Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals.

Broderick, Claire; Cliff, Jacqueline M; Lee, Ji-Sook; Kaforou, Myrsini; Moore, David Aj

Broderick, Claire; Cliff, Jacqueline M; Lee, Ji-Sook; Kaforou, Myrsini; Moore, David Aj.

Afiliación

Broderick C; Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK; TB Centre, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK; Section for Paediatric Infectious Disease, Departmen
Cliff JM; TB Centre, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Lee JS; TB Centre, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Kaforou M; Section for Paediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, W2 1PG, UK.
Moore DA; Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK; TB Centre, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.

Tuberculosis (Edinb) ; 127: 102033, 2021 03.

Article en En | MEDLINE | ID: mdl-33524936

Asunto(s)

Antituberculosos/uso terapéutico; Ensayos de Liberación de Interferón gamma; Tuberculosis Latente/prevención & control; Mycobacterium tuberculosis/patogenicidad; Transcripción Genética/efectos de los fármacos; Adulto; Estudios de Casos y Controles; Femenino; Perfilación de la Expresión Génica; Interacciones Huésped-Patógeno; Humanos; Memoria Inmunológica; Tuberculosis Latente/genética; Tuberculosis Latente/inmunología; Tuberculosis Latente/microbiología; Estudios Longitudinales; Masculino; Mycobacterium tuberculosis/inmunología; Valor Predictivo de las Pruebas; Factores de Tiempo; Transcriptoma; Resultado del Tratamiento; Adulto Joven

Palabras clave

Latent tuberculosis infection; Preventive therapy; Transcriptome

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Tuberculosis Latente / Ensayos de Liberación de Interferón gamma / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Tuberculosis (Edinb) Año: 2021 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google