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Intact Human Immunodeficiency Virus (HIV) Reservoir Estimated by the Intact Proviral DNA Assay Correlates With Levels of Total and Integrated DNA in the Blood During Suppressive Antiretroviral Therapy.
Papasavvas, Emmanouil; Azzoni, Livio; Ross, Brian N; Fair, Matthew; Yuan, Zhe; Gyampoh, Kwasi; Mackiewicz, Agnieszka; Sciorillo, Amanda C; Pagliuzza, Amelie; Lada, Steven M; Wu, Guoxin; Goh, Shih Lin; Bahnck-Teets, Carolyn; Holder, Daniel J; Zuck, Paul D; Damra, Mohammad; Lynn, Kenneth M; Tebas, Pablo; Mounzer, Karam; Kostman, Jay R; Abdel-Mohsen, Mohamed; Richman, Douglas; Chomont, Nicolas; Howell, Bonnie J; Montaner, Luis J.
Afiliación
  • Papasavvas E; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Azzoni L; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Ross BN; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Fair M; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Yuan Z; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Gyampoh K; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Mackiewicz A; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Sciorillo AC; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Pagliuzza A; University of Montreal, Montreal, Canada.
  • Lada SM; Veterans Affairs San Diego Healthcare System and the University of California, San Diego, California, USA.
  • Wu G; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Goh SL; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Bahnck-Teets C; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Holder DJ; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Zuck PD; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Damra M; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Lynn KM; Presbyterian Hospital, University of Pennsylvania hospital, Philadelphia, Pennsylvania, USA.
  • Tebas P; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Mounzer K; Jonathan Lax Immune Disorders Treatment Center, Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, Pennsylvania, USA.
  • Kostman JR; John Bell Health Center, Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, Pennsylvania, USA.
  • Abdel-Mohsen M; Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Richman D; Veterans Affairs San Diego Healthcare System and the University of California, San Diego, California, USA.
  • Chomont N; University of Montreal, Montreal, Canada.
  • Howell BJ; Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Montaner LJ; Wistar Institute, Philadelphia, Pennsylvania, USA.
Clin Infect Dis ; 72(3): 495-498, 2021 02 01.
Article en En | MEDLINE | ID: mdl-33527127
Accurate characterization of the human immunodeficiency virus (HIV) reservoir is imperative to develop an effective cure. HIV was measured in antiretroviral therapy-suppressed individuals using the intact proviral DNA assay (IPDA), along with assays for total or integrated HIV DNA, and inducible HIV RNA or p24. Intact provirus correlated with total and integrated HIV.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos