Theoretical studies of DNA during gel electrophoresis.
Science
; 240(4854): 922-4, 1988 May 13.
Article
en En
| MEDLINE
| ID: mdl-3363374
ABSTRACT
A numerical study of the motion of a long-chain macromolecule in a gel has shown unexpected features. The application of a field appears to induce the chain to contract on itself. This is followed by its "unwinding" into an extended configuration. For long chains, the mobility tends toward a constant, in accord with experiments. For the parameter range used, the observed molecular motion differs strongly from assumptions made in the present theory of electrophoresis.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
ADN
/
Electroforesis
/
Electroforesis en Gel de Agar
/
Conformación de Ácido Nucleico
Idioma:
En
Revista:
Science
Año:
1988
Tipo del documento:
Article