Reactive astrocytes in ALS display diminished intron retention.

Ziff, Oliver J; Taha, Doaa M; Crerar, Hamish; Clarke, Benjamin E; Chakrabarti, Anob M; Kelly, Gavin; Neeves, Jacob; Tyzack, Giulia E; Luscombe, Nicholas M; Patani, Rickie

Ziff, Oliver J; Taha, Doaa M; Crerar, Hamish; Clarke, Benjamin E; Chakrabarti, Anob M; Kelly, Gavin; Neeves, Jacob; Tyzack, Giulia E; Luscombe, Nicholas M; Patani, Rickie.

Afiliación

Ziff OJ; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Taha DM; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Crerar H; National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
Clarke BE; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Chakrabarti AM; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Kelly G; Department of Zoology, Faculty of Science, Alexandria University, Alexandria 21511, Egypt.
Neeves J; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Tyzack GE; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Luscombe NM; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Patani R; Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.

Nucleic Acids Res ; 49(6): 3168-3184, 2021 04 06.

Article en En | MEDLINE | ID: mdl-33684213

Asunto(s)

Empalme Alternativo; Esclerosis Amiotrófica Lateral/genética; Astrocitos/metabolismo; Intrones; Animales; Astrocitos/efectos de los fármacos; Canales de Calcio/genética; Núcleo Celular/genética; Células Cultivadas; Citocinas/farmacología; Citoplasma/genética; Citoplasma/metabolismo; Proteínas de Unión al ADN/genética; Expresión Génica; Humanos; Ratones; Mutación; Superóxido Dismutasa-1/genética; Translocación Genética; Proteína que Contiene Valosina/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Intrones / Astrocitos / Empalme Alternativo / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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