eIF2B conformation and assembly state regulate the integrated stress response.

Schoof, Michael; Boone, Morgane; Wang, Lan; Lawrence, Rosalie; Frost, Adam; Walter, Peter

Schoof, Michael; Boone, Morgane; Wang, Lan; Lawrence, Rosalie; Frost, Adam; Walter, Peter.

Afiliación

Schoof M; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
Boone M; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Wang L; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
Lawrence R; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Frost A; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
Walter P; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.

Elife ; 102021 03 10.

Article en En | MEDLINE | ID: mdl-33688831

Asunto(s)

Factor 2B Eucariótico de Iniciación/química; Estrés Fisiológico/genética; Humanos; Conformación Proteica

Palabras clave

ISR; ISRIB; allostery; biochemistry; cell biology; chemical biology; eIF2; eIF2B; human

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estrés Fisiológico / Factor 2B Eucariótico de Iniciación Límite: Humans Idioma: En Revista: Elife Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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