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Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers.
Li, Meng-Zhu; Meng, Tao; Song, Shan-Shan; Bao, Xu-Bin; Ma, Lan-Ping; Zhang, Ning; Yu, Ting; Zhang, Yong-Liang; Xiong, Bing; Shen, Jing-Kang; Miao, Ze-Hong; He, Jin-Xue.
Afiliación
  • Li MZ; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica,, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Meng T; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
  • Song SS; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
  • Bao XB; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Ma LP; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica,, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang N; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
  • Yu T; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica,, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang YL; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
  • Xiong B; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
  • Shen JK; Department of Medicinal Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Miao ZH; Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica,, Chinese Academy of Sciences, Shanghai, 201203, China.
  • He JX; University of Chinese Academy of Sciences, No.19A Yuquan Road, 100049, Beijing, China.
Invest New Drugs ; 39(5): 1213-1221, 2021 10.
Article en En | MEDLINE | ID: mdl-33710464
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína BRCA1 / Proteína BRCA2 / G-Cuádruplex / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína BRCA1 / Proteína BRCA2 / G-Cuádruplex / Antineoplásicos Límite: Animals / Humans / Male Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article País de afiliación: China