Advancing drug discovery using the power of the human genome.
J Pathol
; 254(4): 418-429, 2021 07.
Article
en En
| MEDLINE
| ID: mdl-33748968
Human genetics plays an increasingly important role in drug development and population health. Here we review the history of human genetics in the context of accelerating the discovery of therapies, present examples of how human genetics evidence supports successful drug targets, and discuss how polygenic risk scores could be beneficial in various clinical settings. We highlight the value of direct-to-consumer platforms in the era of fast-paced big data biotechnology, and how diverse genetic and health data can benefit society. © 2021 23andMe, Inc. The Journal of Pathology published by John Wiley & Sons, Ltd. on behalf of The Pathological Society of Great Britain and Ireland.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Genoma Humano
/
Descubrimiento de Drogas
Límite:
Humans
Idioma:
En
Revista:
J Pathol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos